phenobarbital sodium molecular weight - An Overview

phenobarbital sodium molecular weight - An Overview

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pentobarbital will lower the extent or effect of darunavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.

Contraindicated (one)pentobarbital will lessen the extent or effect of doravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will reduce the level or effect of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

pentobarbital will reduce the level or effect of aprepitant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.

Phenytoin, sodium valproate, valproic acid: The effect of barbiturates on the metabolism of phenytoin appears to become variable. Some investigators report an accelerating effect, although others report no effect. Since the effect of barbiturates to the metabolism of phenytoin is not really predictable, phenytoin and barbiturate blood stages need to be monitored more often if these drugs are offered concurrently.

pentobarbital will lessen the level or effect of maraviroc by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

pentobarbital will lower the extent or effect of methadone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

pentobarbital will lessen the extent or effect of parecoxib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unknown.

pentobarbital will decrease the level or effect of artemether/lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration with powerful CYP3A4 inducers may lead to decreased serum concentrations and loss of antimalarial efficacy

Corticosteroids: Barbiturates surface to enhance the metabolism of exogenous corticosteroids in all probability with the induction of hepatic microsomal enzymes. Patients stabilized on corticosteroid therapy may well need dosage adjustments if barbiturates are included to or withdrawn from their dosage routine.

Sodium valproate and valproic acid surface to reduce barbiturate metabolism; hence, barbiturate blood amounts need to be monitored here and proper dosage adjustments built as indicated.

Contraindicated (one)pentobarbital will reduce the extent or effect of elbasvir/grazoprevir by impacting hepatic/intestinal enzyme CYP3A4 metabolism.

Watch Closely (1)pentobarbital will reduce the level or effect of glecaprevir/pibrentasvir by influencing hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will decrease the extent or effect of capivasertib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Strong or moderate CYP3A inducers reduce capivasertib publicity, which may minimize efficacy.